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Female migraine patient with child

Don't just react to migraine

Help prevent migraine days before they start by taking Emgality just once a month*
*Following an initial loading dose of 240 mg — 2 injections of 120 mg each.

Historically, many preventive migraine medicines were designed for other conditions. Emgality was specifically developed to bind to CGRP, a substance in the brain that may play a key role in migraine, and block its binding to the receptor.

Actor portrayal. Emgality is not indicated for use in children.

CGRP receptor

CGRP=calcitonin gene-related peptide.

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Select Safety Information
Do not use Emgality if you are allergic to galcanezumab-gnlm or any of the ingredients in Emgality.

Emgality can cause high blood pressure or worsening of high blood pressure. Contact your healthcare provider if you have an increase in blood pressure.

Emgality comes in an easy-to-use, self-injectable pen that can be used in the comfort of your home

At first use, 94% of people in a study agreed that the Emgality pen was easy to use, and 96% were confident in their ability to use it

a woman sitting on a bench

Actor portrayal

SAFETY SUMMARY

Warnings -

Do not use Emgality if you are allergic to galcanezumab-gnlm or any of the ingredients in Emgality.

Allergic reactions.

Emgality may cause allergic reactions, such as itching, rash, hives, and trouble breathing. Allergic reactions can happen days after using Emgality. Call your healthcare provider or get emergency medical help right away if you have any of the following symptoms, which may be part of an allergic reaction: swelling of your face, mouth, tongue, or throat, or trouble breathing.

High blood pressure.

High blood pressure or worsening of high blood pressure can happen after receiving Emgality. Contact your healthcare provider if you have an increase in blood pressure.

Raynaud’s phenomenon.

A type of circulation problem can worsen or happen after receiving Emgality. Raynaud’s phenomenon can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red. Contact your healthcare provider if these symptoms occur.

Common side effects

The most common side effects of Emgality are injection site reactions.

These are not all the possible side effects of Emgality. Tell your doctor if you have any side effects.

You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Emgality, discuss these questions with your doctor:

  • Do you have other medical conditions?
  • Do you take other medicines? Tell your doctor about all the prescription and over-the-counter drugs, vitamins, and herbal supplements you take.

Tell your doctor if:

  • You have high blood pressure.
  • You have circulation problems in your fingers and toes.
  • You are pregnant or breastfeeding.
  • Pregnancy Registry: There is a pregnancy registry for women who take Emgality. The purpose of this registry is to collect information about the health of you and your baby. You may enroll yourself by calling 1-833-464-4724 or by visiting www.pregnancyregistry.lilly.com or you may talk to your healthcare provider about how you can take part in this registry.
  • You are under age 18. It is not known if Emgality is safe and effective in children.

How to take

  • Read the Instructions for Use that come with Emgality. There you will find information about how to store, prepare, and inject Emgality.
  • Use Emgality exactly as your doctor says.
  • If you miss a dose, inject it as soon as possible. Then do the following:
    • For migraine: Continue to take Emgality monthly from the date of your last dose.
    • For episodic cluster headache: If your cluster period has not ended, inject Emgality one month after your last dose to get back on a monthly dosing schedule.

Learn more

Emgality is an injectable prescription medicine available as:

  • prefilled single-dose pen with 120 mg/mL solution
  • prefilled single-dose syringe with 120 mg/mL solution
  • prefilled single-dose syringe with 100 mg/mL solution

For more information, go to www.emgality.lilly.com or call 1-800-LillyRx (1-800-545-5979).

This summary provides basic information about Emgality but does not include all information known about this medicine. Read the information that comes with your prescription every time you have a prescription filled. This information does not take the place of talking to your doctor. Be sure to talk to your doctor or other healthcare provider about Emgality and how to take it. Your doctor is the best person to help you decide if Emgality is right for you.

GZ CON COMBO BS 04APR2025

Please see Instructions for Use that come with the device.

Emgality® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates. ©Lilly USA, LLC 2025. All rights reserved.

INDICATIONS

Emgality® (em-GAL-it-e¯ ) is used in adults for:

  • The preventive treatment of migraine. The medicine (120 mg) comes in a prefilled pen or syringe and is taken once a month.
  • The treatment of episodic cluster headache. The medicine (300 mg) comes in three (100 mg) prefilled syringes, which are taken one after the other at the start of a cluster period and then every month until the end of the cluster period.