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Cluster headache

is considered one of the most severe forms of headache

It is thought to affect more than 250,000 adults in the US.

There are 2 types of cluster headache:


  • A period of cluster headache attacks that lasts 7 days to 1 year, separated by a cluster headache-free period of at least 3 months


  • A period of cluster headache attacks that lasts for at least 1 year with cluster headache-free periods lasting less than 3 months

Emgality is not approved for the treatment of chronic cluster headache attacks.

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The length and number of attacks can vary

During a cluster headache cycle, attack frequency can range from once every other day to 8 times a day, and attacks can last anywhere from 15 minutes to up to 3 hours.

Symptoms of cluster headache attack

Along with severe pain felt on one side of the head around the eye and/or temple, people may experience symptoms such as:

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Redness and/or watering of the eye

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Restlessness or agitation

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Runny nose or nasal congestion

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Forehead and facial sweating

Ask your doctor to see if Emgality 300 mg can help reduce the number of your episodic cluster headache attacks.


Warnings -

Do not use Emgality if you are allergic to galcanezumab-gnlm or any of the ingredients in Emgality.

Emgality may cause allergic reactions, such as itching, rash, hives, and trouble breathing. Allergic reactions can happen days after using Emgality. Call your healthcare provider or get emergency medical help right away if you have any of the following symptoms, which may be part of an allergic reaction: swelling of your face, mouth, tongue, or throat, or trouble breathing.

Common side effects

The most common side effects of Emgality are injection site reactions.

These are not all the possible side effects of Emgality. Tell your doctor if you have any side effects.

You can report side effects at 1-800-FDA-1088 or

Before using

Before you use Emgality, discuss these questions with your doctor:

  • Do you have other medical conditions?
  • Do you take other medicines? Tell your doctor about all the prescription and over-the-counter drugs, vitamins, and herbal supplements you take.

Tell your doctor if:

  • You are pregnant or breastfeeding.
  • Pregnancy Registry: There is a pregnancy registry for women who take EMGALITY. The purpose of this registry is to collect information about the health of you and your baby. You may enroll yourself by calling 1-833-464-4724 or by visiting or you may talk to your healthcare provider about how you can take part in this registry.
  • You are under age 18. It is not known if Emgality is safe and effective in children.

How to take

  • Read the Instructions for Use that come with Emgality. There you will find information about how to store, prepare, and inject Emgality.
  • Use Emgality exactly as your doctor says.
  • If you miss a dose, inject it as soon as possible. Then do the following:
    • For migraine: Continue to take Emgality monthly from the date of your last dose.
    • For episodic cluster headache: If your cluster period has not ended, inject Emgality one month after your last dose to get back on a monthly dosing schedule.

Learn more

Emgality is a prescription medicine. For more information, call 1-833-EMGALITY (1-833-364-2548).

This summary provides basic information about Emgality, but does not include all information known about this medicine. Read the information that comes with your prescription every time you have a prescription filled. This information does not take the place of talking to your doctor. Be sure to talk to your doctor or other healthcare provider about Emgality and how to take it. Your doctor is the best person to help you decide if Emgality is right for you.


Please see Instructions for Use that come with the device.


Emgality® (em-GAL-it-ē) is used in adults for:

  • The preventive treatment of migraine. The medicine (120 mg) comes in a prefilled pen or syringe and is taken once a month.
  • The treatment of episodic cluster headache. The medicine (300 mg) comes in three (100 mg) prefilled syringes, which are taken one after the other at the start of a cluster period and then every month until the end of the cluster period.